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Explain the mechanism of CRISPR-Cas9 gene editing and discuss its potential implications for genetic therapy. How does the Cas9 protein distinguish between target and non-target DNA sequences?

Describe the molecular mechanisms of protein folding and misfolding, including the role of chaperones and heat shock proteins. Analyze how misfolding leads to diseases such as Alzheimer's or Parkinson's. Provide a detailed account of the cellular pathways and therapeutic interventions' implications.